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Chronic Inflammatory Demyelinating Polyneuropathy
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a neurological disorder that affects the peripheral nervous system, which includes the nerves outside the brain and spinal cord. CIDP is considered an autoimmune disorder, where the body's immune system mistakenly attacks its own nerves, specifically the myelin sheath, which is the protective covering around nerve fibers.
Key Features of CIDP: Demyelination: The primary problem in CIDP is the loss or damage of the myelin sheath, which slows or disrupts nerve signal transmission.Chronic Nature: Unlike some other forms of neuropathy, CIDP typically progresses over a longer period of time (weeks to months) and can fluctuate in severity.
Symptom Onset and Progression:
Symptoms often begin gradually and progress over time.The condition can be symmetrical, affecting both sides of the body.Common symptoms include weakness, numbness, and tingling, which usually start in the legs and can ascend to the arms.Muscle weakness may be severe enough to cause difficulty walking, and in some cases, may affect respiratory muscles. Main Symptoms:
Weakness: Typically affects the legs first, then may progress to the arms.Sensory Symptoms: Numbness, tingling, or loss of sensation in the hands and feet.Reflex Loss: Diminished or absent deep tendon reflexes (such as knee or ankle reflexes).Fatigue: This is common and can be debilitating for many people with CIDP. Repatha Stopped - Causing neurological issues and the inability to walk
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